NanoNeedling vs. Microneedling: What’s the Difference?
Microneedling has become one of the most in-demand treatments in professional aesthetics for skin rejuvenation, collagen support, and overall skin revitalization. With its growing popularity, a gentler, no-downtime alternative has emerged—Nano Needling, also known as nano infusion therapy.
While both treatments are performed using pen-like devices and share similar goals, there are key differences in how they work, how deep they go, and what skin concerns they best address. Here’s a breakdown to help you understand and communicate the difference clearly.
How Are Microneedling and Nano Needling Similar?
Both treatments:
- Use a pen-style device with an oscillating cartridge
- Support cell turnover and skin rejuvenation
- Help enhance topical product absorption
- Are performed by trained skincare professionals using the MD Needle Pen
But that’s where the similarities end.
What Makes Microneedling Unique?
Microneedling uses a cartridge with 12 sterile, stainless steel needles, which can be adjusted from 0.25 mm up to 2.5 mm, depending on the treatment area and skin condition. This creates controlled micro-channels that reach into the dermis, stimulating the body’s natural response to produce collagen and elastin—key building blocks for firmer, smoother skin.
Microneedling is ideal for:
- Fine lines and wrinkles
- Enlarged pores
- Acne scars and stretch marks
- Skin texture concerns
- Mild to moderate skin laxity
- Hair restoration support
- Hyperpigmentation
Recommended treatment frequency: Once every 4 weeks in a series of 3–6 treatments.
What Makes NanoNeedling Different?
Nano needling is a non-invasive cosmetic treatment that uses a cartridge containing 81 microscopic silicone cones (not metal needles). These cones gently press into the topmost layer of the skin—the epidermis—creating nano-channels to infuse active serums into the skin and encourage a brighter, more refined complexion.
Nano Needling is best for:
- Dull, tired-looking skin
- Mild pigmentation concerns
- Enlarged pores
- Fine lines (early signs)
- Clients who want no downtime or have sensitive skin
Recommended treatment frequency: Weekly or bi-weekly for ongoing skin maintenance and radiance.
Microscopic view of the Tip

Which Treatment Should You Recommend?
Choosing between microneedling and nano needling depends on your client’s skin goals, comfort level, and desired downtime. For deeper results and long-term skin transformation, microneedling is the go-to. For gentle rejuvenation, product infusion, and an immediate glow with zero recovery time, nano needling is ideal.
With the MD Needle Pen, professionals can perform both microneedling and nano needling using interchangeable cartridges—all with one powerful, professional-grade device.
One Device. Two Powerful Options.
Whether your client is ready to tackle deep acne scars or simply wants a radiant glow before an event, MD Needle Pen has the flexibility to deliver. Equip your practice with a dual-purpose device designed for professional results, precision control, and patient satisfaction.
📞 Questions? Call us at (855) 714-0004
💻 Learn more or shop at mdneedlepen.com


